Human CTSE protein (Recombinant) (C-His) (STJP013187)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CTSE-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM MES, 150mM NaCl, pH 5.5. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | CTSE |
| Gene ID | 1510 |
| Uniprot ID | CATE_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser20-Pro396 |
Additional Info
| Post Translational Modifications | Glycosylated. The nature of the carbohydrate chain varies between cell types. In fibroblasts, the proenzyme contains a high mannose-type oligosaccharide, while the mature enzyme contains a complex-type oligosaccharide. In erythrocyte membranes, both the proenzyme and mature enzyme contain a complex-type oligosaccharide. Two forms are produced by autocatalytic cleavage, form I begins at Ile-54, form II begins at Thr-57. |
| Function | May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. |
| Protein Name | Cathepsin E Cleaved Into - Cathepsin E Form I - Cathepsin E Form Ii |
| Database Links | Reactome: R-HSA-2132295 |
| Cellular Localisation | EndosomeThe Proenzyme Is Localized To The Endoplasmic Reticulum And Golgi ApparatusWhile The Mature Enzyme Is Localized To The Endosome |
| Alternative Protein Names | Cathepsin E Cleaved Into - Cathepsin E Form I - Cathepsin E Form Ii proteinCTSE protein |
Information sourced from Uniprot.org