| Short Description : | Recombinant-Human CTHRC1-C-His protein was developed in human using the region Ser31-Lys243. For use in research applications. |
| Host: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | CTHRC1 |
| Gene ID: | 115908 |
| Uniprot ID: | CTHR1_HUMAN |
| Immunogen: | Recombinant Human CTHRC1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence ( Ser31-Lys243 ) of human CTHRC1 (Accession #NP_612464.1) fused with a His tag at the C-terminus. |
| Immunogen Region: | Ser31-Lys243 |
| Immunogen Sequence: | SEIPKGKQKAQLRQREVVDL YNGMCLQGPAGVPGRDGSPG ANGIPGTPGIPGRDGFKGEK GECLRESFEESWTPNYKQCS WSSLNYGIDLGKIAECTFTK MRSNSALRVLFSGSLRLKCR NACCQRWYFTFNGAECSGPL PIEAIIYLDQGSPEMNSTIN IHRTSSVEGLCEGIGAGLVD VAIWVGTCSDYPKGDASTGW NSVSRIIIEELPK |
| Tissue Specificity | Isoform 1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells. |
| Post Translational Modifications | N-glycosylated. |
| Function | May act as a negative regulator of collagen matrix deposition. |
| Protein Name | Collagen Triple Helix Repeat-Containing Protein 1 |
| Database Links | |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Protein Names | Collagen Triple Helix Repeat-Containing Protein 1 proteinCTHRC1 proteinUNQ762 proteinPRO1550 protein |
Information sourced from Uniprot.org
