Human CTGF/CCN2 protein (Recombinant) (His-Tag) (STJP019081)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CTGF/CCN2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCN2 |
| Gene ID | 1490 |
| Uniprot ID | CCN2_HUMAN |
| Accession Number | NP_001892 |
| Immunogen | Human |
| Immunogen Region | 27-349aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. |
| Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. |
| Protein Name | Ccn Family Member 2Cellular Communication Network Factor 2Connective Tissue Growth FactorHypertrophic Chondrocyte-Specific Protein 24Insulin-Like Growth Factor-Binding Protein 8Ibp-8Igf-Binding Protein 8Igfbp-8 |
| Database Links | Reactome: R-HSA-2032785Reactome: R-HSA-8951671 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Protein Names | Ccn Family Member 2 proteinCellular Communication Network Factor 2 proteinConnective Tissue Growth Factor proteinHypertrophic Chondrocyte-Specific Protein 24 proteinInsulin-Like Growth Factor-Binding Protein 8 proteinIbp-8 proteinIgf-Binding Protein 8 proteinIgfbp-8 proteinCCN2 proteinCTGF proteinHCS24 proteinIGFBP8 protein |
Information sourced from Uniprot.org