Human CTGF/CCN2 protein (Recombinant) (C-His&Avi) {Biotin} (STJP020342)
SPECIFICATIONS
HostHEK293 cells
ConjugationBiotin
ImmunogenBiotinylated Recombinant Human CTGF/CCN2 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Gln27-Ala349) of Human CTGF/CCN2 fused with a His and Avi tag at the C-terminal.
General Information
| Short Description | Recombinant-Human CTGF/CCN2-C-His&Avi protein was developed in hek293 cells using the region Gln27-Ala349. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, 200 mM L-arginine, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | CCN2 |
| Gene ID | 1490 |
| Uniprot ID | CCN2_HUMAN |
| Immunogen | Biotinylated Recombinant Human CTGF/CCN2 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Gln27-Ala349) of Human CTGF/CCN2 fused with a His and Avi tag at the C-terminal. |
| Immunogen Region | Gln27-Ala349 |
Additional Info
| Tissue Specificity | Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. |
| Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. |
| Protein Name | Ccn Family Member 2Cellular Communication Network Factor 2Connective Tissue Growth FactorHypertrophic Chondrocyte-Specific Protein 24Insulin-Like Growth Factor-Binding Protein 8Ibp-8Igf-Binding Protein 8Igfbp-8 |
| Database Links | Reactome: R-HSA-2032785Reactome: R-HSA-8951671 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Protein Names | Ccn Family Member 2 proteinCellular Communication Network Factor 2 proteinConnective Tissue Growth Factor proteinHypertrophic Chondrocyte-Specific Protein 24 proteinInsulin-Like Growth Factor-Binding Protein 8 proteinIbp-8 proteinIgf-Binding Protein 8 proteinIgfbp-8 proteinCCN2 proteinCTGF proteinHCS24 proteinIGFBP8 protein |
Information sourced from Uniprot.org