Human CTDSPL protein (Recombinant) (N-His) (STJP006541)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CTDSPL-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CTDSPL |
| Gene ID | 10217 |
| Uniprot ID | CTDSL_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Pro13-Val236 |
Additional Info
| Function | Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. |
| Protein Name | Ctd Small Phosphatase-Like ProteinCtdsp-LikeCarboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 3Nif-Like ProteinNuclear Lim Interactor-Interacting Factor 1Nli-Interacting Factor 1Protein Ya22Hya22Rbsp3Small C-Terminal Domain Phosphatase 3Scp3Small Ctd Phosphatase 3 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Ctd Small Phosphatase-Like Protein proteinCtdsp-Like proteinCarboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 3 proteinNif-Like Protein proteinNuclear Lim Interactor-Interacting Factor 1 proteinNli-Interacting Factor 1 proteinProtein Ya22 proteinHya22 proteinRbsp3 proteinSmall C-Terminal Domain Phosphatase 3 proteinScp3 proteinSmall Ctd Phosphatase 3 proteinCTDSPL proteinC3orf8 proteinNIF1 proteinNIFL proteinSCP3 proteinYA22 protein |
Information sourced from Uniprot.org