Human CSF2RA/GM-CSF R alpha/CD116 protein (Recombinant) (C-hFc) (STJP019959)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human CSF2RA/GM-CSF R alpha/CD116 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu23-Gly320) of Human CSF2RA/GM-CSF R alpha/CD116 (Accession #P15509-1) fused with a C-hFc tag at the
General Information
| Short Description | Recombinant-Human CSF2RA/GM-CSF R alpha/CD116-C-hFc protein was developed in hek293 cells using the region Glu23-Gly320. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | CSF2RA |
| Gene ID | 1438 |
| Uniprot ID | CSF2R_HUMAN |
| Immunogen | Recombinant Human CSF2RA/GM-CSF R alpha/CD116 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu23-Gly320) of Human CSF2RA/GM-CSF R alpha/CD116 (Accession #P15509-1) fused with a C-hFc tag at the |
| Immunogen Region | Glu23-Gly320 |
| Immunogen Sequence | EKSDLRTVAPASSLNVRFDS RTMNLSWDCQENTTFSKCFL TDKKNRVVEPRLSNNECSCT FREICLHEGVTFEVHVNTSQ RGFQQKLLYPNSGREGTAAQ NFSCFIYNADLMNCTWARGP TAPRDVQYFLYIRNSKRRRE IRCPYYIQDSGTHVGCHLDN LSGLTSRNYFLVNGTSREIG IQFFDSLLDTKKIERFNPPS NVTVRCNTTHCLVRWKQPRT YQKLSYLDFQYQLDVHRKN |
Additional Info
| Function | Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. |
| Protein Name | Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit AlphaGm-Csf-R-AlphaGmcsfr-AlphaGmr-AlphaCdw116Cd Antigen Cd116 |
| Database Links | Reactome: R-HSA-512988Reactome: R-HSA-5673001Reactome: R-HSA-5683826Reactome: R-HSA-5688849Reactome: R-HSA-5688890Reactome: R-HSA-912526 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 3: SecretedIsoform 4: SecretedIsoform 6: Secreted |
| Alternative Protein Names | Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit Alpha proteinGm-Csf-R-Alpha proteinGmcsfr-Alpha proteinGmr-Alpha proteinCdw116 proteinCd Antigen Cd116 proteinCSF2RA proteinCSF2R proteinCSF2RY protein |
Information sourced from Uniprot.org