Human CSF-2/GM-CSF protein (Recombinant) (C-His) (STJP002562)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human CSF-2/GM-CSF Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala18-Glu144) of human GM-CSF/CSF2 (Accession #NP_000749.2) fused with a 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human CSF-2/GM-CSF-C-His protein was developed in hek293 cells using the region Ala18-Glu144. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is 30-140 pg/mL, corresponding to a specific activity of 7.14×106-3.33×107units/mg. |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | CSF2 |
| Gene ID | 1437 |
| Uniprot ID | CSF2_HUMAN |
| Immunogen | Recombinant Human CSF-2/GM-CSF Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala18-Glu144) of human GM-CSF/CSF2 (Accession #NP_000749.2) fused with a 6×His tag at the C-terminus. |
| Immunogen Region | Ala18-Glu144 |
| Immunogen Sequence | APARSPSPSTQPWEHVNAIQ EARRLLNLSRDTAAEMNETV EVISEMFDLQEPTCLQTRLE LYKQGLRGSLTKLKGPLTMM ASHYKQHCPPTPETSCATQI ITFESFKENLKDFLLVIPFD CWEPVQE |
Additional Info
| Protein Name | Granulocyte-Macrophage Colony-Stimulating FactorGm-CsfColony-Stimulating FactorCsfMolgramostinSargramostim |
| Database Links | Reactome: R-HSA-512988Reactome: R-HSA-5673001Reactome: R-HSA-6783783Reactome: R-HSA-8939246Reactome: R-HSA-912526 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Granulocyte-Macrophage Colony-Stimulating Factor proteinGm-Csf proteinColony-Stimulating Factor proteinCsf proteinMolgramostin proteinSargramostim proteinCSF2 proteinGMCSF protein |
Information sourced from Uniprot.org