Human CRYAB protein (Recombinant) (C-His) (STJP014348)

Name: Human CRYAB protein (Recombinant) (C-His) (STJP014348)
SKU: STJP014348-100
Price: 604.2 EUR
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP014348-100

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Short Description	Recombinant-Human CRYAB-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications.
Applications	ELISA/WB
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	< 1 EU/µg as determined by LAL test.

Function	May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. In lens epithelial cells, stabilizes the ATP6V1A protein, preventing its degradation by the proteasome.
Protein Name	Alpha-Crystallin B Chain Alpha(B-Crystallin Heat Shock Protein Beta-5 Hspb5 Heat Shock Protein Family B Member 5 Renal Carcinoma Antigen Ny-Ren-27 Rosenthal Fiber Component
Database Links	Reactome: R-HSA-3371571
Cellular Localisation	Cytoplasm Nucleus Secreted Lysosome Translocates To The Nucleus During Heat Shock And Resides In Sub-Nuclear Structures Known As Sc35 Speckles Or Nuclear Splicing Speckles Localizes At The Z-Bands And The Intercalated Disk In Cardiomyocytes Can Be Secreted The Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10 It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion
Alternative Protein Names	Alpha-Crystallin B Chain protein Alpha(B-Crystallin protein Heat Shock Protein Beta-5 protein Hspb5 protein Heat Shock Protein Family B Member 5 protein Renal Carcinoma Antigen Ny-Ren-27 protein Rosenthal Fiber Component protein CRYAB protein CRYA2 protein HSPB5 protein

Information sourced from Uniprot.org