Human CRLF2 protein (Recombinant) (His-Tag) (STJP018129)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CRLF2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CRLF2 |
| Gene ID | 64109 |
| Uniprot ID | CRLF2_HUMAN |
| Accession Number | NP_071431 |
| Immunogen | Human |
| Immunogen Region | 23-231aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells. |
| Function | Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2. Implicated in the development of the hematopoietic system. |
| Protein Name | Cytokine Receptor-Like Factor 2Cytokine Receptor-Like 2Il-XrThymic Stromal Lymphopoietin Protein ReceptorTslp Receptor |
| Database Links | Reactome: R-HSA-1266695 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Protein Names | Cytokine Receptor-Like Factor 2 proteinCytokine Receptor-Like 2 proteinIl-Xr proteinThymic Stromal Lymphopoietin Protein Receptor proteinTslp Receptor proteinCRLF2 proteinCRL2 proteinILXR proteinTSLPR protein |
Information sourced from Uniprot.org