Human CRHR2 protein (Recombinant) (N-His-SUMO) (STJP009643)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CRHR2-N-His-SUMO protein was developed from e.coli for the region N-His-SUMO. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CRHR2 |
| Gene ID | 1395 |
| Uniprot ID | CRFR2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Glu20-Lys108 |
Additional Info
| Function | G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. |
| Protein Name | Corticotropin-Releasing Factor Receptor 2Crf-R-2Crf-R2Crfr-2Corticotropin-Releasing Hormone Receptor 2Crh-R-2Crh-R2 |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-418555Reactome: R-HSA-422085 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Corticotropin-Releasing Factor Receptor 2 proteinCrf-R-2 proteinCrf-R2 proteinCrfr-2 proteinCorticotropin-Releasing Hormone Receptor 2 proteinCrh-R-2 proteinCrh-R2 proteinCRHR2 proteinCRF2R proteinCRH2R protein |
Information sourced from Uniprot.org