Human CRHR2 (Corticotropin Releasing Hormone Receptor 2) Sandwich ELISA Kit (STJE0008144)
SPECIFICATIONS
General Information
| Short Description | This CRHR2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.051ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | CRHR2 |
| Gene ID | 1395 |
| Uniprot ID | CRFR2_HUMAN |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | A N-glycosylation site within the signal peptide impedes its proper cleavage and function. |
| Function | G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. |
| Protein Name | Corticotropin-Releasing Factor Receptor 2Crf-R-2Crf-R2Crfr-2Corticotropin-Releasing Hormone Receptor 2Crh-R-2Crh-R2 |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-418555Reactome: R-HSA-422085 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Corticotropin-Releasing Factor Receptor 2 ELISA kitCrf-R-2 ELISA kitCrf-R2 ELISA kitCrfr-2 ELISA kitCorticotropin-Releasing Hormone Receptor 2 ELISA kitCrh-R-2 ELISA kitCrh-R2 ELISA kitCRHR2 ELISA kitCRF2R ELISA kitCRH2R ELISA kit |
| output |
Information sourced from Uniprot.org