Human CREBZF protein (Recombinant) (His-Tag) (STJP018908)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CREBZF-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) containing 20% Glycerol, 1mM DTT, 0.1mM PMSF |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CREBZF |
| Gene ID | 58487 |
| Uniprot ID | ZHANG_HUMAN |
| Accession Number | NP_001034707 |
| Immunogen | Human |
| Immunogen Region | 1-354aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMRHSLTK LLAASGSNSP TRSESPEPAA TCSLPSDLTR AAAGEEETAA AGSPGRKQQF GDEGELEAGR GSRGGVAVRA PSPEEMEEEA IASLPGEETE DMDFLSGLEL ADLLDPRQPD WHLDPGLSSP GPLSSSGGGS DSGGLWRGDD DDEAAAAEMQ RFSDLLQRLL NGIGGCSSSS DSGSAEKRRR KSPGGGGGGG SGNDNNQA |
Additional Info
| Tissue Specificity | In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lung. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver. |
| Function | Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells. |
| Protein Name | Creb/Atf Bzip Transcription FactorHost Cell Factor-Binding Transcription Factor ZhangfeiHcf-Binding Transcription Factor Zhangfei |
| Database Links | |
| Cellular Localisation | NucleusColocalizes In Promyelocytic Leukemia Protein Nuclear Bodies (Pml-Nb) With Creb3 And Hcfc1 |
| Alternative Protein Names | Creb/Atf Bzip Transcription Factor proteinHost Cell Factor-Binding Transcription Factor Zhangfei proteinHcf-Binding Transcription Factor Zhangfei proteinCREBZF proteinZF protein |
Information sourced from Uniprot.org