Human CPNE1 protein (Recombinant) (N-His & C-His) (STJP014806)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CPNE1-N-His & C-His protein was developed from e.coli and has a target region of N-His & C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM Citrate, 50mM NaCl, 6% Trehalose, 3% Glycine, 5mM Methionine, 0.05% Tween 80, pH 5.0. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | CPNE1 |
| Gene ID | 8904 |
| Uniprot ID | CPNE1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Ala537 |
Additional Info
| Function | Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation.induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. May function in membrane trafficking. Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit. Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL. |
| Protein Name | Copine-1Chromobindin 17Copine I |
| Database Links | Reactome: R-HSA-1483206Reactome: R-HSA-6798695 |
| Cellular Localisation | NucleusCytoplasmCell MembraneTranslocates To The Cell Membrane In A Calcium-Dependent Manner |
| Alternative Protein Names | Copine-1 proteinChromobindin 17 proteinCopine I proteinCPNE1 proteinCPN1 protein |
Information sourced from Uniprot.org