Human CPN1 (Carboxypeptidase N1) Sandwich ELISA Kit (STJE0008107)
SPECIFICATIONS
General Information
| Short Description | This CPN1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.107ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | CPNE1 |
| Gene ID | 8904 |
| Uniprot ID | CPNE1_HUMAN |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in neutrophils (at protein level). Widely expressed. Expressed in the brain. Expressed in neutrophil precursors from bone marrow and peripheral blood. |
| Post Translational Modifications | |
| Function | Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation.induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. May function in membrane trafficking. Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit. Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL. |
| Protein Name | Copine-1Chromobindin 17Copine I |
| Database Links | Reactome: R-HSA-1483206Reactome: R-HSA-6798695 |
| Cellular Localisation | NucleusCytoplasmCell MembraneTranslocates To The Cell Membrane In A Calcium-Dependent Manner |
| Alternative ELISA Names | Copine-1 ELISA kitChromobindin 17 ELISA kitCopine I ELISA kitCPNE1 ELISA kitCPN1 ELISA kit |
| output |
Information sourced from Uniprot.org