Human COTL1 protein (Recombinant) (N-His) (STJP005376)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human COTL1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | COTL1 |
| Gene ID | 23406 |
| Uniprot ID | COTL1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Glu142 |
Additional Info
| Function | Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis. |
| Protein Name | Coactosin-Like Protein |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | CytoplasmCytoskeletonNucleus |
| Alternative Protein Names | Coactosin-Like Protein proteinCOTL1 proteinCLP protein |
Information sourced from Uniprot.org