Human COPR5 (Cooperator Of PRMT5) Sandwich ELISA Kit (STJE0008072)
SPECIFICATIONS
General Information
| Short Description | This COPR5 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.055ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | COPRS |
| Gene ID | 55352 |
| Uniprot ID | COPRS_HUMAN |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression. Plays a role in muscle cell differentiation by modulating the recruitment of PRMT5 to the promoter of genes involved in the coordination between cell cycle exit and muscle differentiation. |
| Protein Name | Coordinator Of Prmt5 And Differentiation StimulatorCooperator Of Prmt5Protein Ttp1 |
| Database Links | Reactome: R-HSA-3214858 |
| Cellular Localisation | Nucleus |
| Alternative ELISA Names | Coordinator Of Prmt5 And Differentiation Stimulator ELISA kitCooperator Of Prmt5 ELISA kitProtein Ttp1 ELISA kitCOPRS ELISA kitC17orf79 ELISA kitCOPR5 ELISA kit |
| output |
Information sourced from Uniprot.org