| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | CLPS |
| Gene ID: | 1208 |
| Uniprot ID: | COL_HUMAN |
| Immunogen: | Recombinant Human Colipase/CLPS Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Met1-Gln112) of human CLPS/Colipase (Accession #NP_001823.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | MEKILILLLVALSVAYAAPG PRGIIINLENGELCMNSAQC KSNCCQHSSALGLARCTSMA SENSECSVKTLYGIYYKCPC ERGLTCEGDKTIVGSITNTN FGICHDAGRSKQ |
| Tissue Specificity | Expressed by the pancreas. |
| Function | Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. Enterostatin has a biological activity as a satiety signal. |
| Protein Name | Colipase |
| Database Links | Reactome: R-HSA-192456Reactome: R-HSA-975634 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Colipase proteinCLPS protein |
Information sourced from Uniprot.org