Human COASY protein (Recombinant) (N-His) (STJP005281)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human COASY-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | COASY |
| Gene ID | 80347 |
| Uniprot ID | COASY_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Pro101-Ile366 |
Additional Info
| Function | Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain.the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation. |
| Protein Name | Bifunctional Coenzyme A SynthaseCoa SynthaseNbpPov-2 Includes - Phosphopantetheine AdenylyltransferaseDephospho-Coa PyrophosphorylasePantetheine-Phosphate AdenylyltransferasePpat - Dephospho-Coa KinaseDpckDephosphocoenzyme A KinaseDpcoak |
| Database Links | Reactome: R-HSA-196783 |
| Cellular Localisation | CytoplasmMitochondrion MatrixThe Protein Is Mainly Present In The Mitochondrial MatrixProbably Anchored To The Inner Mitochondrial MembraneBut Is Also Present In Cell Lysate |
| Alternative Protein Names | Bifunctional Coenzyme A Synthase proteinCoa Synthase proteinNbp proteinPov-2 Includes - Phosphopantetheine Adenylyltransferase proteinDephospho-Coa Pyrophosphorylase proteinPantetheine-Phosphate Adenylyltransferase proteinPpat - Dephospho-Coa Kinase proteinDpck proteinDephosphocoenzyme A Kinase proteinDpcoak proteinCOASY proteinPSEC0106 protein |
Information sourced from Uniprot.org