Human CNTF protein (Recombinant) (His-Tag) (STJP019297)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CNTF-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Bioactivity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.5) containing 1mM DTT, 30% Glycerol, 0.2M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity | Measured in a cell proliferation assay using TF-1 human erythroleukemic cell. The ED50 range ≤ 1ug/ml. |
Target Information
| Gene Symbol | CNTF |
| Gene ID | 1270 |
| Uniprot ID | CNTF_HUMAN |
| Accession Number | NP_000605 |
| Immunogen | Human |
| Immunogen Region | 1-200aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Nervous system. |
| Function | CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. |
| Protein Name | Ciliary Neurotrophic FactorCntf |
| Database Links | Reactome: R-HSA-6788467 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Ciliary Neurotrophic Factor proteinCntf proteinCNTF protein |
Information sourced from Uniprot.org