Human CNMD protein (Recombinant) (N-His) (STJP003382)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CNMD-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CNMD |
| Gene ID | 11061 |
| Uniprot ID | CNMD_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Lys134-Val334 |
Additional Info
| Post Translational Modifications | After cleavage, the post-translationally modified ChM-I is secreted as a glycoprotein. |
| Function | Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization. |
| Protein Name | Leukocyte Cell-Derived Chemotaxin 1Chondromodulin Cleaved Into - Chondrosurfactant ProteinCh-Sp - Chondromodulin-1Chondromodulin-IChm-I |
| Database Links | |
| Cellular Localisation | Chondromodulin-1: SecretedExtracellular SpaceExtracellular MatrixAccumulated In The Inter-Territorial Matrix Of CartilageChondrosurfactant Protein: Endomembrane SystemSingle-Pass Membrane Protein |
| Alternative Protein Names | Leukocyte Cell-Derived Chemotaxin 1 proteinChondromodulin Cleaved Into - Chondrosurfactant Protein proteinCh-Sp - Chondromodulin-1 proteinChondromodulin-I proteinChm-I proteinCNMD proteinCHMI proteinLECT1 proteinMYETS1 protein |
Information sourced from Uniprot.org