Human CLEC2D protein (Recombinant) (N-hFc-Avi) (STJP020320)

Name: Human CLEC2D protein (Recombinant) (N-hFc-Avi) (STJP020320)
SKU: STJP020320-100
Price: 411.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostHEK293 cells

ConjugationUnconjugated

ImmunogenRecombinant Human CLEC2D Protein is expressed from Expi293 with hFc tag and Avi tag at the N-terminal.；It contains Arg60-Val191.

STJP020320-100

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Short Description	Recombinant-Human CLEC2D-N-hFc-Avi protein was developed in hek293 cells using the region Arg60-Val191. For use in research applications.
Host	HEK293 cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method	< 1 EU/Mu g of the protein by LAL method.

Gene Symbol	CLEC2D
Gene ID	29121
Uniprot ID	CLC2D_HUMAN
Immunogen	Recombinant Human CLEC2D Protein is expressed from Expi293 with hFc tag and Avi tag at the N-terminal.；It contains Arg60-Val191.
Immunogen Region	Arg60-Val191

Tissue Specificity	Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T- and B-lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells.
Post Translational Modifications	N-glycosylated.
Function	Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.
Protein Name	C-Type Lectin Domain Family 2 Member D Lectin-Like Nk Cell Receptor Lectin-Like Transcript 1 Llt-1 Osteoclast Inhibitory Lectin
Database Links	Reactome: R-HSA-198933
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein Isoform 2: Endoplasmic Reticulum Isoform 4: Endoplasmic Reticulum
Alternative Protein Names	C-Type Lectin Domain Family 2 Member D protein Lectin-Like Nk Cell Receptor protein Lectin-Like Transcript 1 protein Llt-1 protein Osteoclast Inhibitory Lectin protein CLEC2D protein CLAX protein LLT1 protein OCIL protein

Information sourced from Uniprot.org