Human CLEC2D protein (Recombinant) (N-hFc-Avi) {Biotin} (STJP001674)
SPECIFICATIONS
HostHEK293
ConjugationBiotin
ImmunogenDNA sequence encoding Human CLEC2D including a N-hFc-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
General Information
| Short Description | Recombinant-Human CLEC2D-N-hFc-Avi protein was developed from hek293 and has a target region of N-hFc-Avi. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Dilution Range | Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM |
| Formulation | Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
| Storage Instruction | The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). |
Target Information
| Gene Symbol | CLEC2D |
| Gene ID | 29121 |
| Uniprot ID | CLC2D_HUMAN |
| Immunogen | DNA sequence encoding Human CLEC2D including a N-hFc-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology. |
| Immunogen Region | Arg60-Val191 |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans. |
| Protein Name | C-Type Lectin Domain Family 2 Member DLectin-Like Nk Cell ReceptorLectin-Like Transcript 1Llt-1Osteoclast Inhibitory Lectin |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinIsoform 2: Endoplasmic ReticulumIsoform 4: Endoplasmic Reticulum |
| Alternative Protein Names | C-Type Lectin Domain Family 2 Member D proteinLectin-Like Nk Cell Receptor proteinLectin-Like Transcript 1 proteinLlt-1 proteinOsteoclast Inhibitory Lectin proteinCLEC2D proteinCLAX proteinLLT1 proteinOCIL protein |
Information sourced from Uniprot.org