Human CLCN6 protein (Recombinant) (N-His) (STJP015790)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CLCN6-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | CLCN6 |
| Gene ID | 1185 |
| Uniprot ID | CLCN6_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Glu593-Ile869 |
Additional Info
| Post Translational Modifications | N-glycosylated on several asparagine residues. |
| Function | Voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the late endosome lumen. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters. |
| Protein Name | H(+/Cl(- Exchange Transporter 6Chloride Channel Protein 6Clc-6Chloride Transport Protein 6 |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-6802952 |
| Cellular Localisation | Late Endosome MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | H(+/Cl(- Exchange Transporter 6 proteinChloride Channel Protein 6 proteinClc-6 proteinChloride Transport Protein 6 proteinCLCN6 proteinKIAA0046 protein |
Information sourced from Uniprot.org