Human CLCA4 protein (Recombinant) (N-His) (STJP015926)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CLCA4-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | CLCA4 |
| Gene ID | 22802 |
| Uniprot ID | CLCA4_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser22-Lys301 |
Additional Info
| Post Translational Modifications | The translation product is autoproteolytically cleaved by the metalloprotease domain in the endoplasmic reticulum into a N-terminal and a C-terminal products that remain physically associated with each other. The cleavage is necessary for calcium-activated chloride channel (CaCC) activation activity. |
| Function | May be involved in mediating calcium-activated chloride conductance. |
| Protein Name | Calcium-Activated Chloride Channel Regulator 4Calcium-Activated Chloride Channel Family Member 4Hclca4Calcium-Activated Chloride Channel Protein 2Cacc-2Hcacc-2Chloride Channel Accessory 4 Cleaved Into - Calcium-Activated Chloride Channel Regulator 4 - 110 Kda Form - Calcium-Activated Chloride Channel Regulator 4 - 30 Kda Form |
| Database Links | Reactome: R-HSA-2672351 |
| Cellular Localisation | Cell MembraneSingle-Pass Membrane ProteinApical Cell MembraneSecretedThe C-Terminus 30 Kda Form Is Anchored To The MembraneThe N-Terminus 110 Kda Form Is Released From The Membrane Triggered By An Unknown Stimulus |
| Alternative Protein Names | Calcium-Activated Chloride Channel Regulator 4 proteinCalcium-Activated Chloride Channel Family Member 4 proteinHclca4 proteinCalcium-Activated Chloride Channel Protein 2 proteinCacc-2 proteinHcacc-2 proteinChloride Channel Accessory 4 Cleaved Into - Calcium-Activated Chloride Channel Regulator 4 - 110 Kda Form - Calcium-Activated Chloride Channel Regulator 4 - 30 Kda Form proteinCLCA4 proteinCaCC2 proteinUNQ562 proteinPRO1124 protein |
Information sourced from Uniprot.org