Human CHST15 protein (Recombinant-Active) (N-His) (STJP012180)

Name: Human CHST15 protein (Recombinant-Active) (N-His) (STJP012180)
SKU: STJP012180-100
Price: 503.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP012180-100

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Short Description	Recombinant-Active-Human CHST15-N-His protein was developed from mammalian cells and has a target region of N-His. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	<0.1 EU/Mu g of the protein by the LAL method.
Immunoreactivity	Measured by its ability to transfer sulfate from PAPS to chondroitin sulfate. The specific activity is >100 pmol/min/Mu g, as measured under the described conditions.

Post Translational Modifications	Glycosylated.
Function	Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression.however such results are unclear in vivo.
Protein Name	Carbohydrate Sulfotransferase 15 B-Cell Rag-Associated Gene Protein Hbrag N-Acetylgalactosamine 4-Sulfate 6-O-Sulfotransferase Galnac4s-6st
Database Links	Reactome: R-HSA-2022870
Cellular Localisation	Golgi Apparatus Membrane Single-Pass Type Ii Membrane Protein A Small Fraction May Also Be Present At The Cell Surface Where It Acts As A B-Cell Receptor
Alternative Protein Names	Carbohydrate Sulfotransferase 15 protein B-Cell Rag-Associated Gene Protein protein Hbrag protein N-Acetylgalactosamine 4-Sulfate 6-O-Sulfotransferase protein Galnac4s-6st protein CHST15 protein BRAG protein GALNAC4S6ST protein KIAA0598 protein

Information sourced from Uniprot.org