Human CHRDL1 protein (Recombinant) (N-His) (STJP005940)

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STJP005940
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CHRDL1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CHRDL1
Gene ID: 91851
Uniprot ID: CRDL1_HUMAN
Immunogen Region: Leu22-Arg450
Immunogen: Homo sapiens (Human)
Function Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation. May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.
Protein Name Chordin-Like Protein 1
Neuralin-1
Neurogenesin-1
Ventroptin
Database Links Reactome: R-HSA-201451
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Alternative Protein Names Chordin-Like Protein 1 protein
Neuralin-1 protein
Neurogenesin-1 protein
Ventroptin protein
CHRDL1 protein
NRLN1 protein

Information sourced from Uniprot.org