Human CHCHD3 protein (Recombinant) (N-His) (STJP007497)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CHCHD3-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CHCHD3 |
| Gene ID | 54927 |
| Uniprot ID | MIC19_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser58-Gly227 |
Additional Info
| Function | Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. |
| Protein Name | Micos Complex Subunit Mic19Coiled-Coil-Helix-Coiled-Coil-Helix Domain-Containing Protein 3 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-8949613 |
| Cellular Localisation | Mitochondrion Inner MembraneLipid-AnchorIntermembrane SideCytoplasmNucleusMitochondrion |
| Alternative Protein Names | Micos Complex Subunit Mic19 proteinCoiled-Coil-Helix-Coiled-Coil-Helix Domain-Containing Protein 3 proteinCHCHD3 proteinMIC19 proteinMINOS3 protein |
Information sourced from Uniprot.org