Human CFHR2 protein (Recombinant) (C-His) (STJP013325)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CFHR2-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 200mM NaCl, 2mM EDTA, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | CFHR2 |
| Gene ID | 3080 |
| Uniprot ID | FHR2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Glu19-Lys270 |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism. |
| Protein Name | Complement Factor H-Related Protein 2Fhr-2Ddesk59H Factor-Like 3H Factor-Like Protein 2 |
| Database Links | Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Complement Factor H-Related Protein 2 proteinFhr-2 proteinDdesk59 proteinH Factor-Like 3 proteinH Factor-Like Protein 2 proteinCFHR2 proteinCFHL2 proteinFHR2 proteinHFL3 protein |
Information sourced from Uniprot.org