Human CES2 protein (Recombinant) (N-GST) (STJP003172)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CES2-N-GST protein was developed from e.coli for the region N-GST. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CES2 |
| Gene ID | 8824 |
| Uniprot ID | EST2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | His452-Leu559 |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine. Hydrolyzes aspirin, substrates with large alcohol group and small acyl group and endogenous lipids such as triacylglycerol. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins. |
| Protein Name | Cocaine EsteraseCarboxylesterase 2Ce-2Hce-2Methylumbelliferyl-Acetate Deacetylase 2 |
| Database Links | Reactome: R-HSA-211945Reactome: R-HSA-9749641 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Protein Names | Cocaine Esterase proteinCarboxylesterase 2 proteinCe-2 proteinHce-2 proteinMethylumbelliferyl-Acetate Deacetylase 2 proteinCES2 proteinICE protein |
Information sourced from Uniprot.org