Human Cerebral dopamine neurotrophic factor/CDNF protein (Recombinant) (C-6His) (STJP001925)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human Cerebral dopamine neurotrophic factor/CDNF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln27-Leu187) of human Cerebral dopamine neurotrophic factor/CDNF (Accession #NP_001025
General Information
| Short Description | Recombinant-Human Cerebral dopamine neurotrophic factor/CDNF-C-6His protein was developed in hek293 cells using the region Gln27-Leu187. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | <0.001 EU/Mu g |
Target Information
| Gene Symbol | CDNF |
| Gene ID | 441549 |
| Uniprot ID | CDNF_HUMAN |
| Immunogen | Recombinant Human Cerebral dopamine neurotrophic factor/CDNF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln27-Leu187) of human Cerebral dopamine neurotrophic factor/CDNF (Accession #NP_001025 |
| Immunogen Region | Gln27-Leu187 |
| Immunogen Sequence | QEAGGRPGADCEVCKEFLNR FYKSLIDRGVNFSLDTIEKE LISFCLDTKGKENRLCYYLG ATKDAATKILSEVTRPMSVH MPAMKICEKLKKLDSQICEL KYEKTLDLASVDLRKMRVAE LKQILHSWGEECRACAEKTD YVNLIQELAPKYAATHPKTE L |
Additional Info
| Function | Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra. |
| Protein Name | Cerebral Dopamine Neurotrophic FactorArmet-Like Protein 1Conserved Dopamine Neurotrophic Factor |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Cerebral Dopamine Neurotrophic Factor proteinArmet-Like Protein 1 proteinConserved Dopamine Neurotrophic Factor proteinCDNF proteinARMETL1 protein |
Information sourced from Uniprot.org