Human CEACAM8/CD66b protein (Recombinant) (C-His&Avi) {Biotin} (STJP019961)
SPECIFICATIONS
HostHEK293 cells
ConjugationBiotin
ImmunogenBiotinylated Recombinant Human CEACAM8/CD66b Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln35-Ser319) of Human CEACAM8/CD66b (Accession #P31997) fused with a C-His&Avi tag at the C-terminus.
General Information
| Short Description | Recombinant-Human CEACAM8/CD66b-C-His&Avi protein was developed in hek293 cells using the region Gln35-Ser319. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Formulation | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | CEACAM8 |
| Gene ID | 1088 |
| Uniprot ID | CEAM8_HUMAN |
| Immunogen | Biotinylated Recombinant Human CEACAM8/CD66b Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln35-Ser319) of Human CEACAM8/CD66b (Accession #P31997) fused with a C-His&Avi tag at the C-terminus. |
| Immunogen Region | Gln35-Ser319 |
| Immunogen Sequence | QLTIEAVPSNAAEGKEVLLL VHNLPQDPRGYNWYKGETVD ANRRIIGYVISNQQITPGPA YSNRETIYPNASLLMRNVTR NDTGSYTLQVIKLNLMSEEV TGQFSVHPETPKPSISSNNS NPVEDKDAVAFTCEPETQNT TYLWWVNGQSLPVSPRLQLS NGNRTLTLLSVTRNDVGPYE CEIQNPASANFSDPVTLNVL YGPDAPTISPSDTYYHAGVN LNLSCHAASNPPSQYSWSV |
Additional Info
| Tissue Specificity | Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow. |
| Post Translational Modifications | Glycosylated. |
| Function | Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. |
| Protein Name | Cell Adhesion Molecule Ceacam8Cd67 AntigenCarcinoembryonic Antigen Cgm6Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8Cea Cell Adhesion Molecule 8Non-Specific Cross-Reacting Antigen Nca-95Cd Antigen Cd66b |
| Database Links | Reactome: R-HSA-1566977Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorCell Surface |
| Alternative Protein Names | Cell Adhesion Molecule Ceacam8 proteinCd67 Antigen proteinCarcinoembryonic Antigen Cgm6 proteinCarcinoembryonic Antigen-Related Cell Adhesion Molecule 8 proteinCea Cell Adhesion Molecule 8 proteinNon-Specific Cross-Reacting Antigen Nca-95 proteinCd Antigen Cd66b proteinCEACAM8 proteinCGM6 protein |
Information sourced from Uniprot.org