Human CEACAM6 (CEACAM6) Antibody Pair (STJAP00859)
General Information
| Short Description | This CEACAM6 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R04-6I-7/R09-6I-5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purification |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CEACAM6 |
| Gene ID | 4680 |
| Uniprot ID | CEAM6_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Tissue Specificity | Expressed in neutrophils. Expressed in columnar epithelial and goblet cells of the colon. Expressed in numerous tumor cell lines (at protein level). |
| Post Translational Modifications | Glycosylated. |
| Function | Cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Intercellular adhesion occurs in a calcium- and fibronectin-independent manner. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. Plays a role in neutrophil adhesion to cytokine-activated endothelial cells. Plays a role in cell migration and cell adhesion to endothelial cells. |
| Protein Name | Cell Adhesion Molecule Ceacam6Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6Cea Cell Adhesion Molecule 6Non-Specific Crossreacting AntigenNormal Cross-Reacting AntigenCd Antigen Cd66c |
| Database Links | Reactome: R-HSA-1566977Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorApical Cell MembraneCell SurfaceLocalized To The Apical Glycocalyx Surface |
| Alternative Antibody Pair Names | Cell Adhesion Molecule Ceacam6 antibody pairCarcinoembryonic Antigen-Related Cell Adhesion Molecule 6 antibody pairCea Cell Adhesion Molecule 6 antibody pairNon-Specific Crossreacting Antigen antibody pairNormal Cross-Reacting Antigen antibody pairCd Antigen Cd66c antibody pairCEACAM6 antibody pairNCA antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human CEACAM6 (CEACAM6) Antibody Pair (STJAP00859)
This antibody pair is designed to detect human CEACAM6 (UniProt P40199) and has confirmed reactivity against the human target only.
This antibody pair has been validated for use in ELISA. It is intended for research use only and is not validated for diagnostic or therapeutic applications.
Both antibodies are rabbit monoclonal IgGs supplied unconjugated and formulated in 0.01M PBS at pH 7.2. The clone IDs are R04-6I-7 and R09-6I-5, and both are purified by affinity purification.
Working concentrations are not pre-defined for this pair and must be determined by the end user through titration optimization within their specific experimental setup.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquot and keep at -20°C, and avoid repeated freeze/thaw cycles to maintain activity.
Both antibodies in this pair were raised in rabbit against a recombinant human CEACAM6 protein. No additional immunogen region information is specified for this product.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.