Human CEA (CEA) Antibody Pair (STJAP00663)
General Information
| Short Description | This CEA antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Mouse/Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | 15A12/9H4 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | ELISA 1:1000 |
| Formulation | Liquid in PBS containing 0.09% sodium azide as a preservative./Liquid in PBS containing 0.01% thimerosal as a preservative. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CEACAM5 |
| Gene ID | 1048 |
| Uniprot ID | CEAM5_HUMAN |
| Immunogen | A synthesized peptide derived from CEACAM5 |
Additional Info
| Tissue Specificity | Expressed in columnar epithelial and goblet cells of the colon (at protein level). Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. |
| Post Translational Modifications | Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate. |
| Function | Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression.induces resistance to anoikis of colorectal carcinoma cells. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. |
| Protein Name | Cell Adhesion Molecule Ceacam5Carcinoembryonic AntigenCeaCarcinoembryonic Antigen-Related Cell Adhesion Molecule 5Cea Cell Adhesion Molecule 5Meconium Antigen 100Cd Antigen Cd66e |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-202733 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorApical Cell MembraneCell SurfaceLocalized To The Apical Glycocalyx Surface |
| Alternative Antibody Pair Names | Cell Adhesion Molecule Ceacam5 antibody pairCarcinoembryonic Antigen antibody pairCea antibody pairCarcinoembryonic Antigen-Related Cell Adhesion Molecule 5 antibody pairCea Cell Adhesion Molecule 5 antibody pairMeconium Antigen 100 antibody pairCd Antigen Cd66e antibody pairCEACAM5 antibody pairCEA antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human CEA (CEA) Antibody Pair (STJAP00663)
This antibody pair detects human CEA (CEACAM5, UniProt P06731). Reactivity is confirmed for human samples only.
Both antibodies are supplied as affinity-purified mouse monoclonal IgG1 antibodies at 1 mg/mL in liquid format. The two clones are 15A12 and 9H4, and neither is conjugated, so the user is responsible for labeling the detection antibody as required for their assay.
This pair is validated for ELISA only, at a recommended dilution of 1:1000. No other assay formats are listed in the product documentation.
The two antibodies differ in their preservative: one is formulated in PBS containing 0.09% sodium azide, and the other is formulated in PBS containing 0.01% thimerosal. Researchers should account for these preservatives when designing downstream assay steps, as sodium azide can interfere with enzyme-based detection systems.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquots should be kept at -20°C. Repeated freeze/thaw cycles should be avoided to maintain reagent integrity.
Both antibodies were raised against a synthesized peptide derived from human CEACAM5. No immunogen region is specified in the product documentation.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.