Human CDw293/BMPR1B protein (Recombinant) (C-Fc) (STJP006989)
SPECIFICATIONS
HostMammalian Cells
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CDw293/BMPR1B-C-Fc protein was developed from mammalian cells for the region C-Fc. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | BMPR1B |
| Gene ID | 658 |
| Uniprot ID | BMR1B_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Lys14-Arg126 |
Additional Info
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction. |
| Protein Name | Bone Morphogenetic Protein Receptor Type-1bBmp Type-1b ReceptorBmpr-1bCd Antigen Cdw293 |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Bone Morphogenetic Protein Receptor Type-1b proteinBmp Type-1b Receptor proteinBmpr-1b proteinCd Antigen Cdw293 proteinBMPR1B protein |
Information sourced from Uniprot.org