Human CDKN2C protein (Recombinant) (N-His) (STJP014502)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CDKN2C-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 8.0. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | CDKN2C |
| Gene ID | 1031 |
| Uniprot ID | CDN2C_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Gln168 |
Additional Info
| Function | Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB. |
| Protein Name | Cyclin-Dependent Kinase 4 Inhibitor CCyclin-Dependent Kinase 6 InhibitorP18-Ink4cP18-Ink6 |
| Database Links | Reactome: R-HSA-2559580Reactome: R-HSA-2559582Reactome: R-HSA-2559585Reactome: R-HSA-69231 |
| Cellular Localisation | |
| Alternative Protein Names | Cyclin-Dependent Kinase 4 Inhibitor C proteinCyclin-Dependent Kinase 6 Inhibitor proteinP18-Ink4c proteinP18-Ink6 proteinCDKN2C proteinCDKN6 protein |
Information sourced from Uniprot.org