Human CDH6/Cadherin-6 protein (Recombinant-Active) (C-His) (STJP012034)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human CDH6/Cadherin-6-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Measured by the ability of the Immobilised protein to support the adhesion of human clear cell carcinoma epithelial cells (Caki‑2). When 5 x 10^4 cells/well are added to recombinant human CDH6/Cadherin-6 coated plates (5 µg/mL with 100 µL/well) , >30 |
Target Information
| Gene Symbol | CDH6 |
| Gene ID | 1004 |
| Uniprot ID | CADH6_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr22-Ala615 |
Additional Info
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. |
| Protein Name | Cadherin-6Kidney CadherinK-Cadherin |
| Database Links | Reactome: R-HSA-418990 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Cadherin-6 proteinKidney Cadherin proteinK-Cadherin proteinCDH6 protein |
Information sourced from Uniprot.org