| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: | Measured by the ability of the immobilized protein to support the adhesion of A431 human epithelial carcinoma cells. When 1×105 cells/well are added to rhP-CAD/Fc Chimera coated plates (10 Mu g/mL with 100 Mu L/well) , approximately 50-60% will adher |
| Determination Method: | <1 EU/Mu g |
| Gene Symbol: | CDH3 |
| Gene ID: | 1001 |
| Uniprot ID: | CADH3_HUMAN |
| Immunogen: | Recombinant Human CDH3/P-cadherin Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp108-Gly654) of human CDH3/Cadherin-3 (Accession #NP_001784.2) fused with a 6×His tag at the C-terminus. |
| Immunogen Region: | Asp108-Gly654 |
| Immunogen Sequence: | DWVVAPISVPENGKGPFPQR LNQLKSNKDRDTKIFYSITG PGADSPPEGVFAVEKETGWL LLNKPLDREEIAKYELFGHA VSENGASVEDPMNISIIVTD QNDHKPKFTQDTFRGSVLEG VLPGTSVMQVTATDEDDAIY TYNGVVAYSIHSQEPKDPHD LMFTIHRSTGTISVISSGLD REKVPEYTLTIQATDMDGDG STTTAVAVVEILDANDNAPM FDPQKYEAHVPENAVGHEV |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. |
| Protein Name | Cadherin-3Placental CadherinP-Cadherin |
| Database Links | Reactome: R-HSA-418990 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Cadherin-3 proteinPlacental Cadherin proteinP-Cadherin proteinCDH3 proteinCDHP protein |
Information sourced from Uniprot.org
