Human CDCA7 protein (Recombinant) (N-His) (STJP009025)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CDCA7-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CDCA7 |
| Gene ID | 83879 |
| Uniprot ID | CDCA7_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr246-Ala371 |
Additional Info
| Post Translational Modifications | Phosphorylation at Thr-163 promotes interaction with YWHAE and YWHAZ, dissociation from MYC and sequestration in the cytoplasm. In vitro, phosphorylated at Thr-163 by AKT. |
| Function | Participates in MYC-mediated cell transformation and apoptosis.induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator. |
| Protein Name | Cell Division Cycle-Associated Protein 7Protein Jpo1 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmPredominantly Nuclear With Some Expression Also Seen In The CytoplasmPredominantly Cytoplasmic When Phosphorylated At Thr-163 |
| Alternative Protein Names | Cell Division Cycle-Associated Protein 7 proteinProtein Jpo1 proteinCDCA7 proteinJPO1 protein |
Information sourced from Uniprot.org