Human CD83 protein (Recombinant) (C-Fc) (STJP013404)

Name: Human CD83 protein (Recombinant) (C-Fc) (STJP013404)
SKU: STJP013404-100
Price: 503.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP013404-100

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Short Description	Recombinant-Human CD83-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	< 1 EU/µg as determined by LAL test.

Post Translational Modifications	Glycosylated when expressed on activated dendritic cells.
Function	Transmembrane glycoprotein predominantly found on the surface of many immune cells including dendritic cells or lymphocytes that plays various roles in immune response regulation. Plays an essential role in CD4(+) T-selection, differentiation and stability by regulating the activity of the major E3 ubiquitin ligase responsible for controlling MHCII trafficking MARCHF8. Also inhibits MARCHF1 association with MHCII or CD86 to prevent their ubiquitination and subsequent degradation. In addition, acts as an important modulator of protective responses against acute infections.
Protein Name	Cd83 Antigen Hcd83 B-Cell Activation Protein Cell Surface Protein Hb15 Cd Antigen Cd83
Database Links
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Cd83 Antigen protein Hcd83 protein B-Cell Activation Protein protein Cell Surface Protein Hb15 protein Cd Antigen Cd83 protein CD83 protein

Information sourced from Uniprot.org