Human CD64/FCGR1A protein (Recombinant-Active) (C-His) (STJP012463)

SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
STJP012463-100
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General Information

Short DescriptionRecombinant-Active-Human CD64/FCGR1A-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
ApplicationsELISA/WB
HostMammalian Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ConjugationUnconjugated
Dilution RangeReconstitute in sterile water for a stock solution.
FormulationLyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt.
Endotoxin< 1 EU/ยตg as determined by LAL test.

Target Information

Gene SymbolFCGR1A
Gene ID2209
Uniprot IDFCGR1_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionGln16-Pro288

Additional Info

Post Translational Modifications Phosphorylated on serine residues.
Function High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells.
Protein Name High Affinity Immunoglobulin Gamma Fc Receptor I
Igg Fc Receptor I
Fc-Gamma Ri
Fcri
Fc-Gamma Ria
Fcgammaria
Cd Antigen Cd64
Database Links Reactome: R-HSA-1236978
Reactome: R-HSA-198933
Reactome: R-HSA-2029481
Reactome: R-HSA-2029482
Reactome: R-HSA-2029485
Reactome: R-HSA-877300
Reactome: R-HSA-9664323
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Stabilized At The Cell Membrane Through Interaction With Fcer1g
Alternative Protein Names High Affinity Immunoglobulin Gamma Fc Receptor I protein
Igg Fc Receptor I protein
Fc-Gamma Ri protein
Fcri protein
Fc-Gamma Ria protein
Fcgammaria protein
Cd Antigen Cd64 protein
FCGR1A protein
FCG1 protein
FCGR1 protein
IGFR1 protein

Information sourced from Uniprot.org

Citations

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