Human CD62P/SELP protein (Recombinant) (C-Fc) (STJP013205)

SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
STJP013205-100
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General Information

Short DescriptionRecombinant-Human CD62P/SELP-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
ApplicationsELISA/WB
HostMammalian Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ConjugationUnconjugated
Dilution RangeReconstitute in sterile water for a stock solution.
FormulationLyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin< 1 EU/µg as determined by LAL test.

Target Information

Gene SymbolSELP
Gene ID6403
Uniprot IDLYAM3_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionTrp42-Ala771

Additional Info

Function Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. Mediates cell-cell interactions and cell adhesion via the interaction with integrin alpha-IIb/beta3 (ITGA2B:ITGB3) and integrin alpha-V/beta-3 (ITGAV:ITGB3).
Protein Name P-Selectin
Cd62 Antigen-Like Family Member P
Granule Membrane Protein 140
Gmp-140
Leukocyte-Endothelial Cell Adhesion Molecule 3
Lecam3
Platelet Activation Dependent Granule-External Membrane Protein
Padgem
Cd Antigen Cd62p
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-202733
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names P-Selectin protein
Cd62 Antigen-Like Family Member P protein
Granule Membrane Protein 140 protein
Gmp-140 protein
Leukocyte-Endothelial Cell Adhesion Molecule 3 protein
Lecam3 protein
Platelet Activation Dependent Granule-External Membrane Protein protein
Padgem protein
Cd Antigen Cd62p protein
SELP protein
GMRP protein
GRMP protein

Information sourced from Uniprot.org

Citations

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