Human CD58/LFA-3 protein (Recombinant) (His-Tag) (STJP018995)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP018995
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General Information

Short DescriptionRecombinant-Human CD58/LFA-3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE/Denatured
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolCD58
Gene ID965
Uniprot IDLFA3_HUMAN
Accession NumberNP_001770
ImmunogenHuman
Immunogen Region29-215aa
Immunogen SequenceFSQQIYG VVYGNVTFHV PSNVPLKEVL WKKQKDKVAE LENSEFRAFS SFKNRVYLDT VSGSLTIYNL TSSDEDEYEM ESPNITDTMK FFLYVLESLP SPTLTCALTN GSIEVQCMIP EHYNSHRGLI MYSWDCPMEQ CKRNSTSIYF KMENDLPQKI QCTLSNPLFN TTSSIILTTC IPSSGHSRHR

Additional Info

Function Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Protein Name Lymphocyte Function-Associated Antigen 3
Ag3
Surface Glycoprotein Lfa-3
Cd Antigen Cd58
Database Links Reactome: R-HSA-202733
Reactome: R-HSA-6798695
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Lymphocyte Function-Associated Antigen 3 protein
Ag3 protein
Surface Glycoprotein Lfa-3 protein
Cd Antigen Cd58 protein
CD58 protein
LFA3 protein

Information sourced from Uniprot.org

Citations

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