Human CD57/B3GAT1 protein (Recombinant) (N-His) (STJP006123)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD57/B3GAT1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | B3GAT1 |
| Gene ID | 27087 |
| Uniprot ID | B3GA1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | His25-Ile334 |
Additional Info
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
| Function | Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. |
| Protein Name | Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1Beta-1 -3-Glucuronyltransferase 1Glucuronosyltransferase PGlcat-PUdp-Glcua -Glycoprotein Beta-1 -3-GlucuronyltransferaseGlcuat-P |
| Database Links | Reactome: R-HSA-1971475 |
| Cellular Localisation | Isoform 1: Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinSecretedIsoform 2: Golgi Apparatus MembraneEndoplasmic Reticulum Membrane |
| Alternative Protein Names | Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 proteinBeta-1 -3-Glucuronyltransferase 1 proteinGlucuronosyltransferase P proteinGlcat-P proteinUdp-Glcua -Glycoprotein Beta-1 -3-Glucuronyltransferase proteinGlcuat-P proteinB3GAT1 proteinGLCATP protein |
Information sourced from Uniprot.org