Human CD40 (CD40) Antibody Pair (STJAP00766)
General Information
| Short Description | This CD40 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R16-7B-9/R67-1K-7 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CD40 |
| Gene ID | 958 |
| Uniprot ID | TNR5_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Tissue Specificity | B-cells and in primary carcinomas. |
| Function | Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 5B-Cell Surface Antigen Cd40Bp50Cd40l ReceptorCdw40Cd Antigen Cd40 |
| Database Links | Reactome: R-HSA-198933 P25942-1Reactome: R-HSA-5668541 P25942-1Reactome: R-HSA-5676594 P25942-1 |
| Cellular Localisation | Isoform I: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Ii: Secreted |
| Alternative Antibody Pair Names | Tumor Necrosis Factor Receptor Superfamily Member 5 antibody pairB-Cell Surface Antigen Cd40 antibody pairBp50 antibody pairCd40l Receptor antibody pairCdw40 antibody pairCd Antigen Cd40 antibody pairCD40 antibody pairTNFRSF5 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human CD40 (CD40) Antibody Pair (STJAP00766)
This antibody pair detects human CD40 (UniProt P25942) and has confirmed reactivity against human samples only. It is not validated for use in other species.
Both the capture and detection antibodies are rabbit monoclonal IgGs supplied unconjugated at 1 mg/mL, formulated in 0.01M PBS at pH 7.2, and purified by affinity chromatography. Clone IDs are R16-7B-9 and R67-1K-7 respectively.
This antibody pair is validated for use in ELISA. No other assay formats are listed as validated applications.
Optimal working concentrations are determined by the end user and are not specified in the product data. Titration experiments are recommended to establish the appropriate dilution for each antibody in the intended assay setup.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquot and store at -20°C, and avoid repeated freeze/thaw cycles to preserve activity.
Both antibodies in this pair are supplied unconjugated, so the user is responsible for labeling the detection antibody with an appropriate reporter, such as biotin or an enzyme, prior to use in the assay.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.