Human CD3E&CD3G protein (Recombinant) (C-hFc&Avi) {Biotin} (STJP020017)
SPECIFICATIONS
HostHEK293 cells
ConjugationBiotin
ImmunogenBiotinylated Recombinant Human CD3E&CD3G/CD3 epsilon&CD3 gamma Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp23-Asp126 (CD3E) & Gln23-Ser116 (CD3G) ) of Human CD3E&CD3G/CD3 epsilon&CD3 gamma
General Information
| Short Description | Recombinant-Human CD3E&CD3G-C-hFc&Avi protein was developed in hek293 cells using the region Asp23-Asp126. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Formulation | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Immunogen | Biotinylated Recombinant Human CD3E&CD3G/CD3 epsilon&CD3 gamma Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp23-Asp126 (CD3E) & Gln23-Ser116 (CD3G) ) of Human CD3E&CD3G/CD3 epsilon&CD3 gamma |
| Immunogen Region | Asp23-Asp126 |
| Immunogen Sequence | DGNEEMGGITQTPYKVSISG TTVILTCPQYPGSEILWQHN DKNIGGDEDDKNIGSDEDHL SLKEFSELEQSGYYVCYPRG SKPEDANFYLYLRARVCENC MEMDQSIKGNHLVKVYDYQE DGSVLLTCDAEAKNITWFKD GKMIGFLTEDKKKWNLGSNA KDPRGMYQCKGSQNKSKPLQ VYYRMCQNCIELNAATIS |
Additional Info
| Background | T-cell surface glycoprotein CD3 epsilon&CD3 gamma chain, also known as CD3E&CD3G, are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR) , TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. |
Information sourced from Uniprot.org