Human CD3E&CD3G (Primary Amine Labeling) protein (Recombinant) (C-His) {Biotin} (STJP019887)
SPECIFICATIONS
HostHEK293 cells
ConjugationBiotin
ImmunogenBiotinylated Recombinant Human CD3E&CD3G/CD3 epsilon&CD3 gamma Protein (Primary Amine Labeling) is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp23-Glu120 (CD3E) & Gln23-Asn106 (CD3G) ) of Human CD3E&CD
General Information
| Short Description | Recombinant-Human CD3E&CD3G (Primary Amine Labeling)-C-His protein was developed in hek293 cells using the region Asp23-Glu120. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Formulation | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Immunogen | Biotinylated Recombinant Human CD3E&CD3G/CD3 epsilon&CD3 gamma Protein (Primary Amine Labeling) is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp23-Glu120 (CD3E) & Gln23-Asn106 (CD3G) ) of Human CD3E&CD |
| Immunogen Region | Asp23-Glu120 |
| Immunogen Sequence | DGNEEMGGITQTPYKVSISG TTVILTCPQYPGSEILWQHN DKNIGGDEDDKNIGSDEDHL SLKEFSELEQSGYYVCYPRG SKPEDANFYLYLRARVCEQS IKGNHLVKVYDYQEDGSVLL TCDAEAKNITWFKDGKMIGF LTEDKKKWNLGSNAKDPRGM YQCKGSQNKSKPLQVYYRMC QN |
Additional Info
| Background | T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G, are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR) , TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. |
Information sourced from Uniprot.org