Human CD32a/FCGR2A protein (Recombinant) (His-Tag) (STJP018043)

Name: Human CD32a/FCGR2A protein (Recombinant) (His-Tag) (STJP018043)
SKU: STJP018043
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP018043

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Short Description	Recombinant-Human CD32a/FCGR2A-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.25 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 50% Glycerol, 1mM DTT
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	FCGR2A
Gene ID	2212
Uniprot ID	FCG2A_HUMAN
Accession Number	AAH19931.1
Immunogen	Human
Immunogen Region	34-216aa
Immunogen Sequence	QAAPP KAVLKLEPPW INVLQEDSVT LTCQGARSPE SDSIQWFHNG NLIPTHTQPS YRFKANNNDS GEYTCQTGQT SLSDPVHLTV LSEWLVLQTP HLEFQEGETI MLRCHSWKDK PLVKVTFFQN GKSQKFSRLD PTFSIPQANH SHSGDYHCTG NIGYTLFSSK PVTITVQVPS MGSSSPMG

Tissue Specificity	Found on monocytes, neutrophils and eosinophil platelets.
Post Translational Modifications	Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.
Function	Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Protein Name	Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A Igg Fc Receptor Ii-A Cdw32 Fc-Gamma Rii-A Fc-Gamma-Riia Fcrii-A Cd Antigen Cd32
Database Links	Reactome: R-HSA-2029481 Reactome: R-HSA-2029482 Reactome: R-HSA-2029485 Reactome: R-HSA-6798695 Reactome: R-HSA-9664323
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A protein Igg Fc Receptor Ii-A protein Cdw32 protein Fc-Gamma Rii-A protein Fc-Gamma-Riia protein Fcrii-A protein Cd Antigen Cd32 protein FCGR2A protein CD32 protein FCG2 protein FCGR2A1 protein IGFR2 protein

Information sourced from Uniprot.org