Human CD32A/FCGR2A protein (Recombinant-Active) (C-His) (STJP011859)

Name: Human CD32A/FCGR2A protein (Recombinant-Active) (C-His) (STJP011859)
SKU: STJP011859-100
Price: 604.2 EUR
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP011859-100

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Short Description	Recombinant-Active-Human CD32A/FCGR2A-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	<0.1 EU/Mu g of the protein by the LAL method.
Immunoreactivity	Immobilised recombinant CD32A/FCGR2A at 1 Mu g/mL (100 Mu L/well) can bind biotinylated human IgG1 with a linear range of 30-250 ng/mL.

Post Translational Modifications	Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.
Function	Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Protein Name	Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A Igg Fc Receptor Ii-A Cdw32 Fc-Gamma Rii-A Fc-Gamma-Riia Fcrii-A Cd Antigen Cd32
Database Links	Reactome: R-HSA-2029481 Reactome: R-HSA-2029482 Reactome: R-HSA-2029485 Reactome: R-HSA-6798695 Reactome: R-HSA-9664323
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A protein Igg Fc Receptor Ii-A protein Cdw32 protein Fc-Gamma Rii-A protein Fc-Gamma-Riia protein Fcrii-A protein Cd Antigen Cd32 protein FCGR2A protein CD32 protein FCG2 protein FCGR2A1 protein IGFR2 protein

Information sourced from Uniprot.org