Human CD320 protein (Recombinant) (C-His) (STJP013588)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD320-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 10mM Tris-Citrate, 150mM NaCl, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | CD320 |
| Gene ID | 51293 |
| Uniprot ID | CD320_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser36-Val231 |
Additional Info
| Function | Receptor for transcobalamin saturated with cobalamin (TCbl). Plays an important role in cobalamin uptake. Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal center B cells. Functions as costimulator to promote B cell responses to antigenic stimuli.promotes B cell differentiation and proliferation. Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. |
| Protein Name | Cd320 Antigen8d6 AntigenFdc-Signaling Molecule 8d6Fdc-Sm-8d6Transcobalamin ReceptorTcblrCd Antigen Cd320 |
| Database Links | Reactome: R-HSA-3359485Reactome: R-HSA-9758890 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Cd320 Antigen protein8d6 Antigen proteinFdc-Signaling Molecule 8d6 proteinFdc-Sm-8d6 proteinTranscobalamin Receptor proteinTcblr proteinCd Antigen Cd320 proteinCD320 protein8D6A proteinUNQ198 proteinPRO224 protein |
Information sourced from Uniprot.org