Human CD307a/FCRL1 protein (Recombinant) (N-His) (STJP008998)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD307a/FCRL1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | FCRL1 |
| Gene ID | 115350 |
| Uniprot ID | FCRL1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ala17-Asn293 |
Additional Info
| Post Translational Modifications | Phosphorylated on tyrosines upon activation. |
| Function | Type I transmembrane surface glycoprotein preferentially expressed by B-cells that regulates BCR-mediated signaling responses. Recruits ABL1 as the intracellular effector molecule to enhance B-cell activation. Also plays a negative role by suppressing ERK activation under homeostatic and BCR-stimulated conditions in a GRB2-dependent manner. |
| Protein Name | Fc Receptor-Like Protein 1Fcr-Like Protein 1Fcrl1Fc Receptor Homolog 1Fcrh1Ifgp Family Protein 1Hifgp1Immune Receptor Translocation-Associated Protein 5Cd Antigen Cd307a |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Fc Receptor-Like Protein 1 proteinFcr-Like Protein 1 proteinFcrl1 proteinFc Receptor Homolog 1 proteinFcrh1 proteinIfgp Family Protein 1 proteinHifgp1 proteinImmune Receptor Translocation-Associated Protein 5 proteinCd Antigen Cd307a proteinFCRL1 proteinFCRH1 proteinIFGP1 proteinIRTA5 protein |
Information sourced from Uniprot.org